Molecular Evolutionary Models in Drug Discovery

Download or Read online Molecular Evolutionary Models in Drug Discovery full in PDF, ePub and kindle. This book written by Juan Bueno and published by Academic Press which was released on 22 January 2020 with total pages 192. We cannot guarantee that Molecular Evolutionary Models in Drug Discovery book is available in the library, click Get Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like.

Molecular Evolutionary Models in Drug Discovery
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Publisher : Academic Press
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ISBN : 9780128189290
Pages : 192 pages
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Download or Read Online Molecular Evolutionary Models in Drug Discovery in PDF, Epub and Kindle

Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings. Examines the integration and application of evolutionary models in the pharmaceutical industry to create new drug development platforms Investigates the biotechnological prospecting of secondary metabolites and their potential use in the discovery of new drugs Evaluates the ecosystem of living beings and how its molecular adaptation might improve the success of therapies

Molecular Evolutionary Models in Drug Discovery

Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of

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Phenotypic Drug Discovery

Phenotypic drug discovery has been highlighted in the past decade as an important strategy in the discovery of new medical entities. How many marketed drugs are derived from phenotypic screens? From the most recent examples, what were the factors enabling target identification and validation? This book answers these questions by

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Basic Principles of Drug Discovery and Development

Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such

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Concepts and Experimental Protocols of Modelling and Informatics in Drug Design

Concepts and Experimental Protocols of Modelling and Informatics in Drug Design discusses each experimental protocol utilized in the field of bioinformatics, focusing especially on computer modeling for drug development. It helps the user in understanding the field of computer-aided molecular modeling (CAMM) by presenting solved exercises and examples. The book

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De novo Molecular Design

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Adaptive Systems in Drug Design

A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on

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Molecular Modeling in Drug Design

Since the first attempts at structure-based drug design about four decades ago, molecular modelling techniques for drug design have developed enormously, along with the increasing computational power and structural and biological information of active compounds and potential target molecules. Nowadays, molecular modeling can be considered to be an integral component

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Molecular Docking for Computer Aided Drug Design

Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved

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The Era of Artificial Intelligence  Machine Learning  and Data Science in the Pharmaceutical Industry

The Era of Artificial Intelligence, Machine Learning and Data Science in the Pharmaceutical Industry examines the drug discovery process, assessing how new technologies have improved effectiveness. Artificial intelligence and machine learning are considered the future for a wide range of disciplines and industries, including the pharmaceutical industry. In an environment

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Evolutionary Algorithms in Molecular Design

When trying to find new methods and problem-solving strategies for their research, scientists often turn to nature for inspiration. An excellent example of this is the application of Darwin's Theory of Evolution, particularly the notion of the 'survival of the fittest', in computer programs designed to search for optimal solutions

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Recent updates in molecular Endocrinology and Reproductive Physiology of Fish

This book is dedicated to present different aspects of reproductive physiology and molecular endocrinology of commercially important as well as potential aquaculture fish species. The existing aquaculture generation is looking for species diversification for efficient utilization of available diverse water resources. The knowledge of reproductive physiology of fish will help

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Ancestral Sequence Reconstruction

Ancestral sequence reconstruction is a technique of growing importance in molecular evolutionary biology and comparative genomics. As a powerful tool for testing evolutionary and ecological hypotheses, as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a range of fields.Ancestral Sequence Reconstruction starts

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Biomedical Index to PHS supported Research

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Understanding Protein Dynamics  Binding and Allostery for Drug Design

Download or read online Understanding Protein Dynamics Binding and Allostery for Drug Design written by Guang Hu,Pemra Doruker,Hongchun Li,Ebru Demet Akten, published by Frontiers Media SA which was released on 2021-06-08. Get Understanding Protein Dynamics Binding and Allostery for Drug Design Books now! Available in PDF,

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Molecular Genetic Medicine

Molecular Genetic Medicine, Volume I, provides an overview of the progress in several of the most important areas of modern molecular genetics and medicine. The aim is to present a technical and historical picture of the concept that it is through a thorough understanding of genetics of all kinds of

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