The Oncogenomics Handbook

Download or Read online The Oncogenomics Handbook full in PDF, ePub and kindle. This book written by William J. LaRochelle and published by Springer Science & Business Media which was released on 09 November 2007 with total pages 750. We cannot guarantee that The Oncogenomics Handbook book is available in the library, click Get Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like.

The Oncogenomics Handbook
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Publisher : Springer Science & Business Media
Release Date :
ISBN : 9781592598939
Pages : 750 pages
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An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain genomic databases and how to discover oncological targets from them, how then to advance from the gene and transcript to the level of protein biochemistry, how next to move from the chemical realm to that of the living cell and, ultimately, pursue animal modeling and clinical development. Emerging cancer therapeutics including Ritux an, Erbitux, Gleevec Herceptin, Avastin, ABX-EGF, Velcade, Kepivance, Iressa, Tarceva, and Zevalin are addressed. Highlights include cancer genomics, pharmacogenomics, transcriptomics, gene expression analysis, proteomic and enzymatic cancer profiling technologies, and cellular and animal approaches to cancer target validation.

The Oncogenomics Handbook

An integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following a systems biology approach, the authors explain

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Oncogenomics

This book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly

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Oncogenomics

Oncogenomics: From Basic Research to Precision Medicine offers a thorough survey of precision medicine and its diagnostic and therapeutic applications in oncology. Gathering contributions from leading international researchers in the field, chapters examine recent translational advances in oncogenomic methods and technologies, detailing novel molecular classifications of tumors as well as

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Handbook of Oncogenomics

The accumulation of DNA mutations and epigenetic variations that leads to uncontrolled cell proliferation and formation of neoplasm refers to cancer. It is a genetic disease. The sub branch of genomics that deals with the study of cancer related genes is known as oncogenomics. The primary goal of the discipline

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Oncogenomics and Cancer Proteomics

Oncogenomics and Cancer Proteomics - Novel Approaches in Biomarkers Discovery and Therapeutic Targets in Cancer presents comprehensive reviews of the most common cancers from bench to bedside applications by an international team of experts. This book will contribute to the scientific and medical community by providing up-to-date discoveries of oncogenomics

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Systems and Integrative Approaches in Oncogenomics

Significant progress in technology has allowed systems level molecular profiling of cancer which has created a wealth of unprecedented genomics ('oncogenomics') data. Innovative and integrated approaches are needed to translate this rich information into knowledge. In this dissertation, I have explored 3 such case studies involving high throughput datasets such as

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A Computational Approach for Comparative Oncogenomics Using Mouse Models

Combining this connectivity network with the set of cancer genes identified by the Integration Analysis System is a strategy for rapid and efficient interpretation of the genetic results.

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Translational Oncogenomics and Human Cancer Interactomics  Advanced Techniques and Complex System Dynamic Approaches

Download or read online Translational Oncogenomics and Human Cancer Interactomics Advanced Techniques and Complex System Dynamic Approaches written by I. C. Baianu, published by Unknown which was released on 2011. Get Translational Oncogenomics and Human Cancer Interactomics Advanced Techniques and Complex System Dynamic Approaches Books now! Available in PDF, ePub and

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Systems and Integrative Approaches in Oncogenomics

Download or read online Systems and Integrative Approaches in Oncogenomics written by Gopinath Ganji, published by Unknown which was released on 2009. Get Systems and Integrative Approaches in Oncogenomics Books now! Available in PDF, ePub and Kindle.

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Advances in Biology and Therapy of Multiple Myeloma

Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great

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Biochemistry and Molecular Biology Compendium

This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular

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Applications of Biotechnology in Oncology

Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various “omics” technologies and their application in oncology are

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Critical Issues in Head and Neck Oncology

This book provides an overview of the latest advances in head and neck cancer using a multidisciplinary approach. Commencing with a discussion of epidemiological and diagnostic aspects, including the role of vaccination and key pathological features, the book then follows by examining the role of oncogenomics, proteomics, next generation sequencing

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Molecular Genetics of Liver Neoplasia

Primary liver cancer is the third most deadly and fifth most common cancer worldwide (~500,000 deaths annually), with a sharp increase of incidence in the United States in recent years. Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the major types of primary liver cancer. Risk factors include gender, hepatitis B virus (

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Advances in Biology and Therapy of Multiple Myeloma

Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great

GET BOOK!