Sox2

Download or Read online Sox2 full in PDF, ePub and kindle. This book written by Hisato Kondoh and published by Academic Press which was released on 24 August 2015 with total pages 344. We cannot guarantee that Sox2 book is available in the library, click Get Book button to download or read online books. Join over 650.000 happy Readers and READ as many books as you like.

Sox2
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Publisher : Academic Press
Release Date :
ISBN : 9780128004203
Pages : 344 pages
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Sox2: Biology and Role in Development and Disease offers a thorough discussion of the important role of Sox2 in cellular and developmental processes, aimed at facilitating greater understanding of how Sox2 functions across different disciplines. The book discusses the basic biology of Sox2 to help establish the critical foundational knowledge necessary for deeper molecular and functional analysis. The book also provides insight into how the Sox2 transcription factor plays a key role in pluripotency induction, maintenance, and development. Helpful as a tool to organize new research projects, the book assists with preparing lessons, seminars, and thesis or research papers, thereby circumventing the need to spend hours searching through journal databases. A single source for the basic biology of Sox2, Sox2: Biology and Its Role in Development and Disease provides information on networks, gene regulation, and regulatory function in a number of cell types and tissues types. Discusses the important role of Sox2 in cellular and developmental processes Facilitates a greater understanding of how Sox2 functions across different disciplines Assists in identifying, circumventing and modifying the dynamics of Sox2 in cell types Provides greater understanding of the structure of Sox2 and its gene networks Identifies aspects of phenotypic spectrum uncovered following greater understanding of Sox2 during development

The Role of SOX2 in Human Embryonic Stem Cells

SOX2 is a transcription factor critical for maintenance of the stem cell state. It plays a major role in the development of the central nervous system (CNS), as it is required for the proliferation and maintenance of neural stem cells as well as neurogenesis. In this work, I show that

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Sox2

Sox2: Biology and Role in Development and Disease offers a thorough discussion of the important role of Sox2 in cellular and developmental processes, aimed at facilitating greater understanding of how Sox2 functions across different disciplines. The book discusses the basic biology of Sox2 to help establish the critical foundational knowledge

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Sox2 Defines Distinct Functional Classes of Stem Cells

Download or read online Sox2 Defines Distinct Functional Classes of Stem Cells written by Kevin Allen D'Amour, published by Unknown which was released on 2002. Get Sox2 Defines Distinct Functional Classes of Stem Cells Books now! Available in PDF, ePub and Kindle.

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The Role of SOX2 in Colon Cancer Progression

SRY (sex determining region Y)-box 2 (SOX2) is one the embryonic stem cell transcription factors that is capable of reprogramming adult differentiated cells into an induced pluripotent cell. SOX2 is amplified in various types of epithelial cancers and its high its expression correlates with poor prognosis and decreased patient survival.

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The Roles of Sox2 and Sox18 in Hair Type Specification and Pigmentation

This dissertation, "The Roles of Sox2 and Sox18 in Hair Type Specification and Pigmentation" by N S, Michelle, Chan, 陳雁璇, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been

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Sox2 and Inner Ear Development

This dissertation, "Sox2 and Inner Ear Development" by Junchang, Li, 李俊畅, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting

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Genetic Analyses of the Roles of Sox2 and Sox18 in Mouse Hair Development and Growth

This dissertation, "Genetic Analyses of the Roles of Sox2 and Sox18 in Mouse Hair Development and Growth" by Siu-yin, Bryan, Ho, 何兆賢, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has

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Stem Cell Transcription Factor SOX2 in Synovial Sarcoma and Other Soft Tissue Tumors

Soft tissue tumors, as an important oncology domain, entail different entities and are challenging regarding diagnosis and therapy. Here, we focused on synovial sarcoma alongside with other soft tissue tumors and specifically analyzed the expression and amplification of the gene SOX2 which has the full name SRY (sex determining region

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Function of Sox2 as a Transcriptional Repressor

Sox2 is one of the earliest known transcription factors to be expressed during development of the nervous system (Rex et al., 1997; Silvia Brunelli, 2003; Wang et al., 2006b; Dee et al., 2008). Ectodermal cells expressing Sox2 have the potential to differentiate into nerve cells. Cells expressing Sox2 are specified to a neural

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Tissue Specific Transcriptional Regulation of Sox2

This dissertation, "Tissue-specific Transcriptional Regulation of Sox2" by Yiu-fai, Angus, Lee, 李耀輝, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the

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The Role of SOX2 in Colon Cancer Progression

SRY (sex determining region Y)-box 2 (SOX2) is one the embryonic stem cell transcription factors that is capable of reprogramming adult differentiated cells into an induced pluripotent cell. SOX2 is amplified in various types of epithelial cancers and its high its expression correlates with poor prognosis and decreased patient survival.

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ROLE OF ALDH   SOX2 AS TUMOUR

This dissertation, "The Role of ALDH and SOX2 as Tumour Initiating Cell Markers in Non-small Cell Lung Cancer" by Tung-yung, Chui, 崔董庸, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has

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Sox2 Co occupies Distal Enhancer Elements with Cell type specific POU Factors to Specify Cell Identity in Embryonic Stem Cells and Neural Precursor Cells

Sox2 is a master regulator of two distinct cellular states, that of pluripotent embryonic stem cells (ESCs) and multipotent neural progenitor cells (NPCs), but what common or distinct roles Sox2 may play in these cell types not fully understood. Further, the molecular mechanisms by which Sox2 can specify two distinct

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Inducing ASPA Expression in Astroglia and the Role of SOX2 in Glial Cell Development

Canavan disease (CD) is an autosomal recessive neurodegenerative disorder that begins in infancy and causes death by early childhood. CD is typified by a loss of white matter and astrogliosis in the brain, which are caused by inactivating mutations in the gene that encodes aspartoacylase (ASPA). Normally, ASPA metabolizes N-acetyl-L-aspartic

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Stem Cells and Cancer

Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (

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